Egg Aging

Worried about Egg Aging? Do not fear, when Male Pheromones Are Here! Check out!

Healthcare

The latest North-western University study mentions that male pheromones could be the solution for aging eggs of female animals.

The researchers have made use of small, transparent roundworm C. elegans, which comes across as one of the well-established model organisms generally used in biology-related research. With female roundworms being exposed to the male pheromones, aging of egg cells of females could be slowed down, thereby resulting in a much healthier progeny.

Postponing the Death of Embryo

It was found that the above-mentioned exposure did decrease the death of embryo almost twofold, but also decreased abnormalities in embryo of the surviving offspring twofold. The egg cells, under microscope, did look healthier and younger, whereas with aging the same cells look tiny. As such, integrated pest management pheromones are expected to cause further pharmacological interventions that would mitigate infertility issues in the humans by enhancing quality of egg cells and procrastinating the reproductive aging.

As per Ilya Ruvinsky (from Northwestern), one of the very first symptoms of biological aging is receding quality of the reproductive cells, which, in turn, results in reduced fertility, thereby increasing the incidence of fetal defects inclusive of miscarriages, and ultimately, loss of fertility. So, by every criterion that one could be thought of, the male pheromones did render eggs better.

The paper containing these findings was published on May 16 in the “Proceedings of the National Academy of Sciences”. Ruvinsky is one of the research professors of molecular biosciences at Weinberg College of Arts and Sciences of Northwestern. Erin Aprison, a research associate in Ruvinsky’s laboratory, is the first author of the paper. The co-authors are David Angeles-Albores and Svetlana Dzitoyeva.

Even though exposure to male pheromones on the continuous basis worked the best, the shorter exposure did improve egg quality on the whole. As per Ruvinksy does believe that the result could be better explained by the shifting energy budgets of the animals.

Pheromones are the chemicals who act outside the body. They, in fact, inform the animals about the way to budget the finite energy. When there arise situations like conditions not being feasible to reproduction, the female animals would end up spending energy and resources in maintaining the body health, inclusive of neurons, muscles, intestines, and various other reproductive organs. As sensing the male pheromones does trigger downstream signalling from nervous system to the body’s rest part, thereby chasing female animals to enhance the reproductive health. As a result, better eggs are obtained but body decays better.

Glycobiology

Glycobiology is also used herein. It could be referred to as the study of biosynthesis, structure, biology, and evolution of saccharides (better known as carbohydrates, glycans, sugar chains), which are broadly distributed in the nature and also of proteins recognizing them.

An interesting thing to know over here is that when the female roundworms do spend more energy on reproducing, they do produce more number of egg precursors from the stem cells. At the same time, it needs to be noted that in a counterproductive move, majority of these cells actually perished.

Though concrete results are yet to come, researchers are expressing their content regarding the primary results obtained above.

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